Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer

Christopher G. Willett, Yves Boucher, Emmanuelle di Tomaso, +20

Nature Medicine

AngiogenesisMedicineHuman Rectal CancerImmunologyPathology +7

Vascular Normalization by Vascular Endothelial Growth Factor Receptor 2 Blockade Induces a Pressure Gradient Across the Vasculature and Improves Drug Penetration in Tumors

Ricky T. Tong, Yves Boucher, Sergey V. Kozin, +3

Cancer Research

Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation

Frank Winkler, Sergey V. Kozin, Ricky T. Tong, +9

Cancer Cell

Neuro-oncologyVascular NormalizationNuclear MedicineRadiation TherapyGlioma +7

Hypoxia-Inducible mir-210 Regulates Normoxic Gene Expression Involved in Tumor Initiation

Xin Huang, Lianghao Ding, Kevin L. Bennewith, +6

Molecular Cell

Systems BiologyMedicineTumor InitiationMicrorna DetectionSmall Rna +8

Effect of Vascular Normalization by Antiangiogenic Therapy on Interstitial Hypertension, Peritumor Edema, and Lymphatic Metastasis: Insights from a Mathematical Model

Rakesh K. Jain, Ricky T. Tong, Lance L. Munn

Cancer Research

Blocking Platelet-Derived Growth Factor-D/Platelet-Derived Growth Factor Receptor β Signaling Inhibits Human Renal Cell Carcinoma Progression in an Orthotopic Mouse Model

Lei Xu, Ricky T. Tong, David Cochran, +1

Cancer Research

A genetic Xenopus laevis tadpole model to study lymphangiogenesis

Annelii Ny, Marta Koch, Martin Schneider, +22

Nature Medicine

BiologyDevelopmental BiologyDevelopmental GeneticsLymphatic SystemMorphogenesis +3

Two-photon fluorescence correlation microscopy reveals the two-phase nature of transport in tumors

George Alexandrakis, Edward B. Brown, Ricky T. Tong, +4

Nature Medicine

Fluorescence MicroscopyTissue ImagingEngineeringMicroscopyBiomedical Imaging +6

A Minimal Peptide Scaffold for β-Turn Display:  Optimizing a Strand Position in Disulfide-Cyclized β-Hairpins

Andrea G. Cochran, Ricky T. Tong, Melissa A. Starovasnik, +4

Journal of the American Chemical Society

Protein AssemblyPeptide EngineeringMolecular BiologyPeptide ScienceAnalytical Ultracentrifugation +17

Robust 3-D Modeling of Vasculature Imagery Using Superellipsoids

James Tyrrell, Emmanuelle di Tomaso, Daniel G. Fuja, +4

IEEE Transactions on Medical Imaging