Concepedia

Molecular and Genetic Crosstalks between mTOR and ERRα Are Key Determinants of Rapamycin-Induced Nonalcoholic Fatty Liver

Cédric Chaveroux, Lillian J. Eichner, Catherine R. Dufour, Aymen Shatnawi, Arkady Khoutorsky, Guillaume Bourque, Nahum Sonenberg, Vincent Giguère

Cell Metabolism · 2013 · 154 citations · 39 references

DOIFull text

Open access

Concepts

References

39

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim, Mondira Kundu, Benoı̂t Viollet et al. · Nature Cell Biology · 2011 · 7K citations · Full text

, , +12

Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB

Dos D. Sarbassov, Siraj M. Ali, Shomit Sengupta et al. · Molecular Cell · 2006 · 2.6K citations · Full text

, , +6

Termination of autophagy and reformation of lysosomes regulated by mTOR

Li Yu, Christina McPhee, Lixin Zheng et al. · Nature · 2010 · 1.6K citations · Full text

, , +10

mTOR controls mitochondrial oxidative function through a YY1–PGC-1α transcriptional complex

John T. Cunningham, Joseph T. Rodgers, Daniel H. Arlow et al. · Nature · 2007 · 1.5K citations

, , +14

SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth

Thomas Porstmann, Cláudio R. Santos, B Griffiths et al. · Cell Metabolism · 2008 · 1.4K citations · Full text

, , +16