Cláudio R. Santos

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

Marco Gerlinger, Andrew J. Rowan, Stuart Horswell et al. · New England Journal of Medicine · 2012 · 7.8K citations · Full text

Medicine, Cancer Biology, Oncology +14

SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth

Thomas Porstmann, Cláudio R. Santos, B Griffiths et al. · Cell Metabolism · 2008 · 1.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

Marco Gerlinger, Stuart Horswell, James Larkin et al. · Nature Genetics · 2014 · 1.3K citations · Full text

Medicine, Genetics, Molecular Genetics +13

Functional Metabolic Screen Identifies 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 4 as an Important Regulator of Prostate Cancer Cell Survival

Susana R�os, Cláudio R. Santos, Sofia Moco et al. · Cancer Discovery · 2012 · 201 citations

Life Sciences, Biochemistry, Oncology +17

SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair

Nnennaya Kanu, Eva Grönroos, Pierre Martinez et al. · Oncogene · 2015 · 179 citations · Full text

Medicine, Genetics, Oncology +17