Concepedia

Loss of the LAT Adaptor Converts Antigen-Responsive T Cells into Pathogenic Effectors that Function Independently of the T Cell Receptor

Michaël Mingueneau, Romain Roncagalli, Claude Grégoire, Adrien Kissenpfennig, Arkadiusz Miążek, Cristel Archambaud, Ying Wang, Pierre Perrin, Elodie Bertosio, Amandine Sansoni,

Immunity · 2009 · 108 citations · 45 references

Open access

Concepts

Life SciencesCell BiologyImmunologyCellular ImmunologyImmunopathologySignal TransductionAntigen RecognitionCell-mediated ImmunityEffector T Cell FunctionT Cell ActivationT Cell BiologyT Cell DifferentiationAdaptor Protein Function In T Cell SignalingAntigen Recognition By Effector T CellsT Cell ImmunologyT Cell-mediated Immune ResponseT-cell Immune ResponsesT-cell Mediated Immune ResponseT-cell Mediated Responses

References

45

Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

Jeong Kim, Jeffrey P. Rasmussen, Alexander Y. Rudensky · Nature Immunology · 2006 · 1.8K citations

Life Sciences, Genetics, Immunology +14

Plat-E: an efficient and stable system for transient packaging of retroviruses

S. Morita, T Kojima, Toshio Kitamura · Gene Therapy · 2000 · 1.7K citations

Life Sciences, Biology, Biotechnology +9

Differential T Cell Costimulatory Requirements in CD28-Deficient Mice

Arda Shahinian, Klaus Pfeffer, Kelvin P. Lee et al. · Science · 1993 · 1.3K citations

Life Sciences, Cell Biology, Immunology +17

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

Hua Gu, Yong‐Rui Zou, Klaus Rajewsky · Cell · 1993 · 999 citations

Life Sciences, Genetics, Molecular Biology +16

Dynamics and Function of Langerhans Cells In Vivo

Adrien Kissenpfennig, Sandrine Henri, Bertrand Dubois et al. · Immunity · 2005 · 909 citations · Full text

Life Sciences, Biology, Immunology +11