Visualization of the earliest steps of γδ T cell development in the adult thymus

Immo Prinz, Amandine Sansoni, Adrien Kissenpfennig, +3

Nature Immunology

Developmental BiologyAdult ThymusLymphocyte DevelopmentImmunologyEarliest Steps +5

Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor–independent TCR signaling hub

Romain Roncagalli, Simon Hauri, Frédéric Di Fiore, +14

Nature Immunology

Surface Receptor Cd6Signal TransductionMedicineImmune RegulationImmunology +10

Loss of the LAT Adaptor Converts Antigen-Responsive T Cells into Pathogenic Effectors that Function Independently of the T Cell Receptor

Michaël Mingueneau, Romain Roncagalli, Claude Grégoire, +12

Immunity

Autoimmune DiseaseFunction IndependentlyAdaptive Immune SystemImmunologyAntigen Processing +10

The proline-rich sequence of CD3ε controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes

Michaël Mingueneau, Amandine Sansoni, Claude Grégoire, +5

Nature Immunology

Preselection Cd4+cd8+ ThymocytesAutoimmune DiseaseProline-rich SequenceImmunologyAntigen Processing +7

Meningeal macrophages protect against viral neuroinfection

Julie Rebejac, Elisa Eme‐Scolan, Laurie Arnaud, +20

Immunity

NeurovirologyMedicineImmunologyAntiviral ResponseVirology +5

Design, immunogenicity, and efficacy of a pan-sarbecovirus dendritic-cell targeting vaccine

Séverin Coléon, Aurélie Wiedemann, Mathieu Surénaud, +25

EBioMedicine

STAT6 Deletion Converts the Th2 Inflammatory Pathology Afflicting <i> Lat <i>Y136F</i> </i> Mice into a Lymphoproliferative Disorder Involving Th1 and CD8 Effector T Cells

Cristel Archambaud, Amandine Sansoni, Michaël Mingueneau, +4

The Journal of Immunology

Deletion of the LIME adaptor protein minimally affects T and B cell development and function

Claude Grégoire, S̆árka S̆ı́mová, Ying Wang, +10

European Journal of Immunology

Lymphocyte DevelopmentAdaptive Immune SystemGeneticsT-regulatory CellImmunology +19