Concepedia

ARAP3 Is a PI3K- and Rap-Regulated GAP for RhoA

Sonja Krugmann, Roger Williams, Len Stephens, Phillip T. Hawkins

Current Biology · 2004 · 123 citations · 13 references

DOIFull text

Open access

Concepts

References

13

Matrix adhesion and Ras transformation both activate a phosphoinositide 3‐OH kinase and protein kinase B/Akt cellular survival pathway

Asim Khwaja, Pablo Rodriguez‐Viciana, Stefan Wennström et al. · The EMBO Journal · 1997 · 1K citations · Full text

, , +16

Crystal Structure and Functional Analysis of Ras Binding to Its Effector Phosphoinositide 3-Kinase γ

Michael E. Pacold, Sabine Suire, Olga Perišić et al. · Cell · 2000 · 627 citations · Full text

, , +17

P-Rex1, a PtdIns(3,4,5)P3- and Gβγ-Regulated Guanine-Nucleotide Exchange Factor for Rac

Heidi C. E. Welch, W. John Coadwell, Christian D. Ellson et al. · Cell · 2002 · 485 citations · Full text

, , +4

RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1

Koko Katagiri, Akito Maeda, Mika Shimonaka et al. · Nature Immunology · 2003 · 456 citations

, , +14

Direct Interaction of the Rho GDP Dissociation Inhibitor with Ezrin/Radixin/Moesin Initiates the Activation of the Rho Small G Protein

Kazuo Takahashi, Takuya Sasaki, Akiko Mammoto et al. · Journal of Biological Chemistry · 1997 · 428 citations · Full text

, , +15