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The Small-Molecule Inhibitor BI 2536 Reveals Novel Insights into Mitotic Roles of Polo-like Kinase 1

Péter Lénárt, Mark Petronczki, Martin Steegmaier, B. Fiore, Jesse Lipp, Matthias Hoffmann, Wolfgang J. Rettig, Norbert Kraut, Jan‐Michael Peters

Current Biology · 2007 · 677 citations · 43 references

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43

Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen

Thomas U. Mayer, Tarun M. Kapoor, Stephen J. Haggarty et al. · Science · 1999 · 1.7K citations

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Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

Claire Ditchfield, Victoria Johnson, Anthony Tighe et al. · The Journal of Cell Biology · 2003 · 1.2K citations · Full text

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The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore–microtubule attachment and in maintaining the spindle assembly checkpoint

Silke Hauf, Richard W. Cole, Sabrina LaTerra et al. · The Journal of Cell Biology · 2003 · 1.2K citations · Full text

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VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo

Elizabeth A. Harrington, David Bebbington, Jeffrey R. Moore et al. · Nature Medicine · 2004 · 954 citations · Full text

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BI 2536, a Potent and Selective Inhibitor of Polo-like Kinase 1, Inhibits Tumor Growth In Vivo

Martin Steegmaier, Matthias Hoffmann, Anke Baum et al. · Current Biology · 2007 · 849 citations · Full text

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