The Small-Molecule Inhibitor BI 2536 Reveals Novel Insights into Mitotic Roles of Polo-like Kinase 1

Péter Lénárt, Mark Petronczki, Martin Steegmaier, +6

Current Biology

Signal TransductionMitotic RolesCell DivisionSignaling PathwayMedicine +10

Histone H3 serine 10 phosphorylation by Aurora B causes HP1 dissociation from heterochromatin

Toru Hirota, Jesse Lipp, Ban‐Hock Toh, +1

Nature

ChromatinHistone H3Chromatin StructureChromatin RemodelingNatural Sciences +10

Wapl Controls the Dynamic Association of Cohesin with Chromatin

Stephanie Kueng, Björn Hegemann, Beate H. Peters, +4

Cell

ChromatinChromatin StructureChromatin RemodelingNatural SciencesGenetics +7

Integrative analysis of pooled CRISPR genetic screens using MAGeCKFlute

Binbin Wang, Mei Wang, Wubing Zhang, +16

Nature Protocols

Natural SciencesGeneticsMolecular BiologyGenetic EngineeringGenome Engineering +5

SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis

Matthias Muhar, Anja Ebert, Tobias Neumann, +17

Science

GeneticsMolecular BiologyGene Regulatory NetworkDirect TargetsRegulatory Pathways +14

Rec8 Phosphorylation by Casein Kinase 1 and Cdc7-Dbf4 Kinase Regulates Cohesin Cleavage by Separase during Meiosis

V.L. Katis, Jesse Lipp, Richard Imre, +6

Developmental Cell

Dbf4-Dependent Cdc7 Kinase Links DNA Replication to the Segregation of Homologous Chromosomes in Meiosis I

Joao Matos, Jesse Lipp, Aliona Bogdanova, +5

Cell

ChromatinGenome InstabilityCell DivisionMedicineNatural Sciences +10

Aurora B controls the association of condensin I but not condensin II with mitotic chromosomes

Jesse Lipp, Toru Hirota, Ina Poser, +1

Journal of Cell Science

CytogeneticsGeneticsMolecular BiologyMolecular GeneticsAurora B +17

P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates

Miriam Sansó, Rebecca S. Levin, Jesse Lipp, +11

Genes & Development

Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells

Simone Lieb, Silvia Blaha-Ostermann, Elisabeth Kamper, +17

eLife

CytogeneticsGeneticsPathologyCancer BiologyTumor Biology +20