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Bortezomib (PS-341) in Relapsed or Refractory Extensive Stage Small Cell Lung Cancer: A Southwest Oncology Group Phase II Trial (S0327)

Primo N. Lara, Kari Chansky, Angela M. Davies, Wilbur A. Franklin, Paul H. Gumerlock, Perry P. Guaglianone, James N. Atkins, Nichole C. Farneth, Philip C. Mack, John J. Crowley,

Journal of Thoracic Oncology · 2006 · 54 citations · 24 references

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References

24

Proteasome inhibitors: a novel class of potent and effective antitumor agents.

Julian Adams, Vito J. Palombella, Edward A. Sausville et al. · PubMed · 1999 · 1.5K citations

, , +14

Activation in vitro of NF-κB" by phosphorylation of its inhibitor IκB"

Sankar Ghosh, David Baltimore · Nature · 1990 · 1.2K citations

, , +8

Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB

Thomas Henkel, Thomas Machleidt, Irit Alkalay et al. · Nature · 1993 · 1.1K citations

, , +12

Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB

Cun-Yu Wang, James C. Cusack, Rong Liu et al. · Nature Medicine · 1999 · 994 citations

, , +14

Enhanced chemosensitivity to CPT-11 with proteasome inhibitor PS-341: implications for systemic nuclear factor-kappaB inhibition.

James C. Cusack, Rong Liu, Michael E. Houston et al. · PubMed · 2001 · 548 citations

, , +16