Concepedia

Novel pyridine derivatives as potent and selective CB2 cannabinoid receptor agonists

Guo‐Hua Chu, Christopher T. Saeui, Karin Worm, Damian G. Weaver, Robert L. Broadrup, Joel Cassel, Robert N. DeHaven, Christopher J. LaBuda, Michael Koblish, Bernice L. Brogdon,

Bioorganic & Medicinal Chemistry Letters · 2009 · 13 citations · 9 references

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9

Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes

R. Scott Obach · Drug Metabolism and Disposition · 1999 · 1.2K citations

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CB <sub>2</sub> cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids

Mohab Ibrahim, Frank Porreca, Josephine Lai et al. · Proceedings of the National Academy of Sciences · 2005 · 514 citations · Full text

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Phosphorus in organic synthesis—VII

Kunihiro Ninomiya, Takayuki Shioiri, Susumu Yamada · Tetrahedron · 1974 · 364 citations

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Selective Activation of Cannabinoid CB2 Receptors Suppresses Hyperalgesia Evoked by Intradermal Capsaicin

Andrea G. Hohmann, Jesse N. Farthing, A. M. Zvonok et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 121 citations

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Discovery of 2-[(2,4-Dichlorophenyl)amino]- <i>N</i> -[(tetrahydro- 2 <i>H</i> -pyran-4-yl)methyl]-4-(trifluoromethyl)- 5-pyrimidinecarboxamide, a Selective CB2 Receptor Agonist for the Treatment of Inflammatory Pain

Gerard M.P. Giblin, Celestine T. O’Shaughnessy, Alan Naylor et al. · Journal of Medicinal Chemistry · 2007 · 120 citations · Full text

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