Guo‐Hua Chu - Concepedia

Author

Guo‐Hua Chu

Cubist Pharmaceuticals (United States)

Also Known As

Guo-Hua Chu, Guohua Chu, Guo‐Hua Chu, Houssin, R.

Publications

940

Citations

H-Index

Concepts

All Affiliations

Cubist Pharmaceuticals (United States)Duquesne University Shanghai Institute of Materia Medica Chinese Academy of Sciences Mylan (United States)

About

Guo‐Hua Chu is an author at Cubist Pharmaceuticals (United States) specializing in pharmacology, drug discovery, and medicine.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	12	14	373
2	Biochemistry	7	7	184
3	Natural Sciences	5	5	159
4	Health Sciences	1	1	24
5	Biomolecular Engineering	1	1	17

Guo‐Hua Chu

Publications

886

Citations

H-Index

Page 1

	Year	Citations
Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections Bin Liu, Robert E. Lee Trout, Guo‐Hua Chu, Journal of Medicinal Chemistry	2019	281
Potent, Orally Bioavailable Delta Opioid Receptor Agonists for the Treatment of Pain: Discovery of<i>N</i>,<i>N</i>-Diethyl-4-(5-hydroxyspiro[chromene-2,4′-piperidine]-4-yl)benzamide (ADL5859) Bertrand Le Bourdonnec, Rolf T. Windh, Christopher W. Ajello, Journal of Medicinal Chemistry	2008	89
Synthesis of (±)-Epibatidine and Its Analogues Donglu Bai, Rui Xu, Guo‐Hua Chu, The Journal of Organic Chemistry Combinatorial ChemistryMedicinal ChemistryBioorganic ChemistryBiochemistryNatural Sciences	1996	88
Spirocyclic Delta Opioid Receptor Agonists for the Treatment of Pain: Discovery of<i>N</i>,<i>N</i>-Diethyl-3-hydroxy-4-(spiro[chromene-2,4′-piperidine]-4-yl) Benzamide (ADL5747) Bertrand Le Bourdonnec, Rolf T. Windh, Lara K. Leister, Journal of Medicinal Chemistry	2009	83
Development of potent non-estrogenic estrone sulfatase inhibitors Pui‐Kai Li, Guo‐Hua Chu, JingPing Guo, Steroids MedicinePharmacotherapyPharmacologyInhibitory ActivitySteroid Metabolism	1998	51
Development of (p-O-sulfamoyl)-N-alkanoyl-phenylalkyl amines as non-steroidal estrone sulfatase inhibitors Aparna Kolli, Guo‐Hua Chu, Michael E. Rhodes, The Journal of Steroid Biochemistry and Molecular Biology Medicinal Chemistry-N-alkanoyl-phenylalkyl AminesMedicinePharmacotherapyDrug Development	1999	35
Total synthesis of (+)-Indolizidine 195 B and (+)-Monomorine Guy Solladié, Guo‐Hua Chu Tetrahedron Letters PharmacologyTotal SynthesisOrganic ChemistryNatural Product SynthesisSynthetic Chemistry	1996	31
Total synthesis of (±) epibatidine Rui Xu, Guo‐Hua Chu, Donglu Bai Tetrahedron Letters BiosynthesisBioorganic ChemistryTotal SynthesisPharmacologySynthetic Chemistry	1996	29
Novel malonamide derivatives as potent κ opioid receptor agonists Guo‐Hua Chu, Minghua Gu, Joel Cassel, Bioorganic & Medicinal Chemistry Letters Molecular PharmacologyNovel Malonamide DerivativesMedicinePharmacological AgentNeuropharmacology	2007	27
Synthesis and analgesic activity of Epibatidine analogues Rui Xu, Donglu Bai, Guo‐Hua Chu, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryPain MedicineMedicinePharmacological AgentPain Management	1996	26

Page 1