Christopher W. Ajello

Potent, Orally Bioavailable Delta Opioid Receptor Agonists for the Treatment of Pain: Discovery of<i>N</i>,<i>N</i>-Diethyl-4-(5-hydroxyspiro[chromene-2,4′-piperidine]-4-yl)benzamide (ADL5859)

Bertrand Le Bourdonnec, Rolf T. Windh, Christopher W. Ajello et al. · Journal of Medicinal Chemistry · 2008 · 89 citations · Full text

Spirocyclic Delta Opioid Receptor Agonists for the Treatment of Pain: Discovery of<i>N</i>,<i>N</i>-Diethyl-3-hydroxy-4-(spiro[chromene-2,4′-piperidine]-4-yl) Benzamide (ADL5747)

Bertrand Le Bourdonnec, Rolf T. Windh, Lara K. Leister et al. · Journal of Medicinal Chemistry · 2009 · 83 citations · Full text

Nascent structure–activity relationship study of a diastereomeric series of kappa opioid receptor antagonists derived from CJ-15,208

Roland E. Dolle, Mathieu Michaut, Blanca Martínez‐Teipel et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 32 citations · Full text

Molecular Pharmacology, Diastereomeric Series, Biochemistry +10

CB2 selective sulfamoyl benzamides: Optimization of the amide functionality

Christopher W. Ajello, Karin Worm, Bertrand Le Bourdonnec et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 17 citations · Full text

Organic Chemistry, Amide Functionality, Chemistry +2

Arylacetamide κ opioid receptor agonists with reduced cytochrome P450 2D6 inhibitory activity

Bertrand Le Bourdonnec, Christopher W. Ajello, Pamela R. Seida et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 15 citations · Full text

Molecular Pharmacology, Inhibitory Activity, Biochemistry +11