Bernice L. Brogdon

Direct Plasma Sample Injection in Multiple-Component LC−MS−MS Assays for High-Throughput Pharmacokinetic Screening

Jing‐Tao Wu, Hang Zeng, Mingxin Qian et al. · Analytical Chemistry · 1999 · 150 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

Potent, Orally Bioavailable Delta Opioid Receptor Agonists for the Treatment of Pain: Discovery of<i>N</i>,<i>N</i>-Diethyl-4-(5-hydroxyspiro[chromene-2,4′-piperidine]-4-yl)benzamide (ADL5859)

Bertrand Le Bourdonnec, Rolf T. Windh, Christopher W. Ajello et al. · Journal of Medicinal Chemistry · 2008 · 90 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Spirocyclic Delta Opioid Receptor Agonists for the Treatment of Pain: Discovery of<i>N</i>,<i>N</i>-Diethyl-3-hydroxy-4-(spiro[chromene-2,4′-piperidine]-4-yl) Benzamide (ADL5747)

Bertrand Le Bourdonnec, Rolf T. Windh, Lara K. Leister et al. · Journal of Medicinal Chemistry · 2009 · 85 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

Pharmacokinetics and Pharmacodynamics of DPC 333 ((2R)-2-((3R)-3-Amino-3{4-[2-methyl-4-quinolinyl) methoxy] phenyl}-2-oxopyrrolidinyl)-N-hydroxy-4-methylpentanamide)), a Potent and Selective Inhibitor of Tumor Necrosis Factor α-Converting Enzyme in Rodents, Dogs, Chimpanzees, and Humans

Mingxin Qian, Stephen A. Bai, Bernice L. Brogdon et al. · Drug Metabolism and Disposition · 2007 · 53 citations

Medicine, Pharmacokinetics, Pharmacology +12

N-in-1 Dosing Pharmacokinetics in Drug Discovery: Experience, Theoretical and Practical Considerations

Kan He, Mingxin Qian, Harvey Wong et al. · Journal of Pharmaceutical Sciences · 2007 · 29 citations

Pharmacy, Pharmacokinetics, Pharmacology +8