Direct Plasma Sample Injection in Multiple-Component LC−MS−MS Assays for High-Throughput Pharmacokinetic Screening

Jing‐Tao Wu, Hang Zeng, Mingxin Qian, +2

Analytical Chemistry

ImmunologyPharmacodynamic ModelingPre-clinical PharmacologyGas ChromatographyBioanalysis +20

The catfish liver-expressed antimicrobial peptide 2 (LEAP-2) gene is expressed in a wide range of tissues and developmentally regulated

Baolong Bao, Eric Peatman, Peng Xu, +4

Molecular Immunology

Developmental BiologyProtein ExpressionPathogenesisWide RangePeptide Therapeutic +4

Hepato-protective effect of resveratrol against acetaminophen-induced liver injury is associated with inhibition of CYP-mediated bioactivation and regulation of SIRT1–p53 signaling pathways

Ying Wang, Yiming Jiang, Xiaomei Fan, +6

Toxicology Letters

Hepato-protective EffectHepatologyMedicineLiver PhysiologyPathology +7

Hepato-protective effects of six schisandra lignans on acetaminophen-induced liver injury are partially associated with the inhibition of CYP-mediated bioactivation

Yiming Jiang, Xiaomei Fan, Ying Wang, +5

Chemico-Biological Interactions

Schisandra LignansAllergyHepatologyMedicineLiver Physiology +10

Identification of 2-{2-[2-(5-Bromo-2- methoxyphenyl)-ethyl]-3-fluorophenyl}-4,5-dihydro-1<i>H</i>-imidazole (ML00253764), a Small Molecule Melanocortin 4 Receptor Antagonist That Effectively Reduces Tumor-Induced Weight Loss in a Mouse Model

Tricia J. Vos, Andrei Caracoti, L. McGlothan Jennifer, +15

Journal of Medicinal Chemistry

Food IntakeTumor BiologyGastrointestinal Peptide HormoneTranslational PharmacologyObesity +21

High‐speed liquid chromatography/tandem mass spectrometry using a monolithic column for high‐throughput bioanalysis

Jing‐Tao Wu, Hang Zeng, Yuzhong Deng, +1

Rapid Communications in Mass Spectrometry

EngineeringBiological Mass SpectrometryHigh‐throughput BioanalysisBiomedical EngineeringMonolithic Columns +22

Schisandrol B protects against acetaminophen-induced acute hepatotoxicity in mice via activation of the NRF2/ARE signaling pathway

Yiming Jiang, Ying Wang, Huasen Tan, +6

Acta Pharmacologica Sinica

InflammationAllergyHepatologyMedicineLiver Physiology +8

Allyl isothiocyanate ameliorates lipid accumulation and inflammation in nonalcoholic fatty liver disease <i>via</i> the Sirt1/AMPK and NF-κB signaling pathways

Chunxiao Li, Jianguo Gao, Xingyong Wan, +9

World Journal of Gastroenterology

BET Bromodomain Proteins Mediate Downstream Signaling Events following Growth Factor Stimulation in Human Lung Fibroblasts and Are Involved in Bleomycin-Induced Pulmonary Fibrosis

Xiaoyan Tang, Ruoqi Peng, Yonglin Ren, +12

Molecular Pharmacology

Schisandrol B protects against cholestatic liver injury through pregnane X receptors

Hang Zeng, Yiming Jiang, Pan Chen, +9

British Journal of Pharmacology