Joel Cassel

Loperamide (ADL 2-1294), an Opioid Antihyperalgesic Agent with Peripheral Selectivity

Diane L. DeHaven‐Hudkins, Luz Cortes Burgos, Joel Cassel et al. · Journal of Pharmacology and Experimental Therapeutics · 1999 · 147 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth

Troy E. Messick, Garry R. Smith, Samantha S. Soldan et al. · Science Translational Medicine · 2019 · 124 citations · Full text

Life Sciences, Molecular Biology, Oncology +15

Targeted MDM2 Degradation Reveals a New Vulnerability for p53-Inactivated Triple-Negative Breast Cancer

Clare M. Adams, Ramkrishna Mitra, You‐Cai Xiao et al. · Cancer Discovery · 2023 · 107 citations · Full text

Medicine, Molecular Biology, Oncology +16

Fragile X protein mitigates TDP-43 toxicity by remodeling RNA granules and restoring translation

Alyssa N. Coyne, Shizuka Yamada, Bhavani B. Siddegowda et al. · Human Molecular Genetics · 2015 · 96 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17

Targeting ACSS2 with a Transition-State Mimetic Inhibits Triple-Negative Breast Cancer Growth

Katelyn D. Miller, Katherine Pniewski, Caroline Perry et al. · Cancer Research · 2021 · 96 citations · Full text

Medicine, Oncology, Pharmacology +13