Loperamide (ADL 2-1294), an Opioid Antihyperalgesic Agent with Peripheral Selectivity

Manual of pharmacologic calculations with computer programs

International Journal of Biochemistry · 1988 · 1.5K citations

Pharmacy, Clinical Pharmacokinetics, Pharmacology +12

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs.

Alfred H. Schinkel, Els Wagenaar, Carla A.A.M. Mol et al. · Journal of Clinical Investigation · 1996 · 1.3K citations · Full text

Medicine, Pharmacokinetics, Pharmacology +15

Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.

K Raynor, Hyesik Kong, Yong Chen et al. · Molecular Pharmacology · 1994 · 663 citations · Full text

Medicine, Pharmacology, Molecular Pharmacology +16

Analgesic Effect of Intraarticular Morphine after Arthroscopic Knee Surgery

Christoph Stein, Karin Comisel, E. HAIMERL et al. · New England Journal of Medicine · 1991 · 595 citations

Medicine, Orthopaedic Surgery, Orthopedic Surgery +16

Opioids from immunocytes interact with receptors on sensory nerves to inhibit nociception in inflammation.

Christoph Stein, A.H.S. Hassan, Ryszard Przewłocki et al. · Proceedings of the National Academy of Sciences · 1990 · 594 citations · Full text

Life Sciences, Immunology, Pharmacology +17