Concepedia

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

N. Li, Andreas Batzer, Roger J. Daly, Vijay Yajnik, Edward Y. Skolnik, Pierre Teilhard de Chardin, Dafna Bar‐Sagi, Benjamin Margolis, Joseph Schlessinger

Nature · 1993 · 962 citations · 27 references

DOI

Concepts

References

27

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

Eve J. Lowenstein, Roger J. Daly, Andreas Batzer et al. · Cell · 1992 · 1.7K citations · Full text

, , +17

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

Maria Rozakis-Adcock, Jane McGlade, Geraldine Mbamalu et al. · Nature · 1992 · 993 citations

, , +15

ras mediates nerve growth factor receptor modulation of three signal-transducing protein kinases: MAP kinase, Raf-1, and RSK

Kenneth W. Wood, Charlyn Sarnecki, Thomas M. Roberts et al. · Cell · 1992 · 934 citations

, , +16

Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

Linda S. Mulcahy, Mark R. Smith, Dennis W. Stacey · Nature · 1985 · 909 citations

, , +16

Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase

Michael A. Simon, David D.L. Bowtell, G.Steven Dodson et al. · Cell · 1991 · 864 citations

, , +12