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Evolution from heterozygous to homozygous KIT mutation in gastrointestinal stromal tumor correlates with the mechanism of mitotic nondisjunction and significant tumor progression

Somatic VariantHomozygous Kit MutationGastrointestinal OncologyTumor HeterogeneityGeneticsPathologyGastrointestinal Stromal TumorsGastrointestinal PathologySignificant Tumor ProgressionCancer GeneticsMitotic NondisjunctionMedicineTumor Biology