Research on Stability of Synthetic Folic Acid

Abstract

This paper is mainly to investigate the stability of synthetic folic acid under different conditions, including pH, temperature, light, and the presence of antioxidants. The results show that folic acid gives a good stability in the buffer of pH 8.05~10.40, whose reservation ratio can reach more than 93.1% in 72 h, while the preservation ratio of folic acid reduce to 23% in the buffer of pH1.95~6.40. Moreover, folic acid has a good stability in the buffer of pH 5.39~10.40, after water bath at 100°C for 2 h. Folic acid exhibits a good stability under the condition of weak illumination intensity. Increasing illumination intensity promotes a decrease in FA concentration. The combination of antioxidants Vitamin C (VC) and sodium citrate displays a significant effect on protecting folic acid from oxidation.