Chymase Participates in Chronic Dermatitis by Inducing Eosinophil Infiltration

Two types of human mast cells that have distinct neutral protease compositions.

Anne‐Marie Irani, Norman M. Schechter, Shirley S. Craig et al. · Proceedings of the National Academy of Sciences · 1986 · 1K citations · Full text

Life Sciences, Immunology, Pathology +13

Detection of MCT and MCTC types of human mast cells by immunohistochemistry using new monoclonal anti-tryptase and anti-chymase antibodies.

A M Irani, T R Bradford, Christopher L. Kepley et al. · Journal of Histochemistry & Cytochemistry · 1989 · 407 citations · Full text

Medicine, Immunology, Pathology +12

Cathepsin G Activates Protease-activated Receptor-4 in Human Platelets

Gilberto R. Sambrano, Wei Huang, Tatjana R. Faruqi et al. · Journal of Biological Chemistry · 2000 · 342 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase.

Hitoshi Mizutani, Norman M. Schechter, Gerald S. Lazarus et al. · The Journal of Experimental Medicine · 1991 · 320 citations · Full text

Life Sciences, Cell Biology, Immunology +16

Repeated elicitation of contact hypersensitivity induces a shift in cutaneous cytokine milieu from a T helper cell type 1 to a T helper cell type 2 profile

Hideki Kitagaki, Natsuki Ono, K. Hayakawa et al. · The Journal of Immunology · 1997 · 246 citations

Life Sciences, Dermatology, Immunology +17