Design, synthesis and molecular modeling study of acylated 1,2,4-triazole-3-acetates with potential anti-inflammatory activity

Synthesis and anti-inflammatory activity of 1-acylthiosemicarbazides, 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazole-3-thiones

Erhan Palaska, Gülay Şahin, Pelin Kelicen et al. · Il Farmaco · 2002 · 494 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Design of 5-(3,5-di-tert-butyl-4-hydroxyphenyl)-1,3,4-thiadiazoles, -1,3,4-oxadiazoles, and -1,2,4-triazoles as orally active, nonulcerogenic antiinflammatory agents

Michael D. Mullican, Michael W. Wilson, David T. Conner et al. · Journal of Medicinal Chemistry · 1993 · 372 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Ester and Amide Derivatives of the Nonsteroidal Antiinflammatory Drug, Indomethacin, as Selective Cyclooxygenase-2 Inhibitors

Amit S. Kalgutkar, Alan B. Marnett, Brenda C. Crews et al. · Journal of Medicinal Chemistry · 2000 · 312 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities

Diane H. Boschelli, David T. Connor, Dirk A. Bornemeier et al. · Journal of Medicinal Chemistry · 1993 · 202 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Synthesis and anti-inflammatory activity of some [4,6-(4-substituted aryl)-2-thioxo-1,2,3,4-tetrahydro-pyrimidin-5-yl]-acetic acid derivatives

Sushilkumar S. Bahekar, Devanand B. Shinde · Bioorganic & Medicinal Chemistry Letters · 2004 · 165 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11