Michael W. Wilson

A genomic mutational constraint map using variation in 76,156 human genomes

Siwei Chen, Laurent C. Francioli, Julia K. Goodrich et al. · Nature · 2023 · 1.1K citations · Full text

Medicine, Genetics, Evolutionary Biology +8

Design of 5-(3,5-di-tert-butyl-4-hydroxyphenyl)-1,3,4-thiadiazoles, -1,3,4-oxadiazoles, and -1,2,4-triazoles as orally active, nonulcerogenic antiinflammatory agents

Michael D. Mullican, Michael W. Wilson, David T. Conner et al. · Journal of Medicinal Chemistry · 1993 · 372 citations · Full text

Combinatorial Chemistry, Pharmaceutical Science, Log P +16

A genome-wide mutational constraint map quantified from variation in 76,156 human genomes

Siwei Chen, Laurent C. Francioli, Julia K. Goodrich et al. · 2022 · 322 citations · Full text

Gene Constraint Metrics, Genetics, Genetic Epidemiology +23

X-ray Structural and Biological Evaluation of a Series of Potent and Highly Selective Inhibitors of Human Coronavirus Papain-like Proteases

Yahira M. Báez-Santos, Scott J. Barraza, Michael W. Wilson et al. · Journal of Medicinal Chemistry · 2014 · 273 citations · Full text

Highly Selective Inhibitors, Medicinal Chemistry, Homologous Plp2 Enzyme +15

Whole-Exome Sequencing Identifies Causative Mutations in Families with Congenital Anomalies of the Kidney and Urinary Tract

Amelie T. van der Ven, Dervla M. Connaughton, Hadas Ityel et al. · Journal of the American Society of Nephrology · 2018 · 202 citations