Enzyme analysis of the polyketide synthase leads to the discovery of a novel analog of the antibiotic α-lipomycin

Avermectins, New Family of Potent Anthelmintic Agents: Producing Organism and Fermentation

Richard W. Burg, Brinton M. Miller, Jerome Birnbaum et al. · Antimicrobial Agents and Chemotherapy · 1979 · 940 citations · Full text

Medicine, Microbiology, Pharmacology +16

Organization of the biosynthetic gene cluster for the polyketide anthelmintic macrolide avermectin in <i>Streptomyces</i> <i>avermitilis</i>

Haruo Ikeda, Tomoko Nonomiya, Masayo Usami et al. · Proceedings of the National Academy of Sciences · 1999 · 349 citations · Full text

Life Sciences, Microbiology, Molecular Biology +12

Metabolic products of microorganisms. 77. Studies on the mechanism of action of boromycin.

W. Pache, Hans Zähner · PubMed · 1969 · 277 citations

Life Sciences, Biochemistry, Microbiology +13

Biosynthetic Gene Cluster for the Polyenoyltetramic Acid α-Lipomycin

C. Bihlmaier, Elissa Welle, Carsten Hofmann et al. · Antimicrobial Agents and Chemotherapy · 2006 · 80 citations · Full text

Pharmacy, Biochemistry, Molecular Biology +15

Broad Substrate Specificity of the Loading Didomain of the Lipomycin Polyketide Synthase

Satoshi Yuzawa, Clara Eng, Leonard Katz et al. · Biochemistry · 2013 · 42 citations

Life Sciences, Biochemistry, Microbiology +17