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IRAK-4 inhibitors. Part II: A structure-based assessment of imidazo[1,2-a]pyridine binding

George M. Buckley, T.A. Ceska, Joanne L. Fraser, Lewis Gowers, Colin R. Groom, Alícia P. Higueruelo, Kerry Jenkins, Stephen R. Mack, Trevor Morgan, David M. Parry,

Bioorganic & Medicinal Chemistry Letters · 2008 · 52 citations · 6 references

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Crystal Structures of IRAK-4 Kinase in Complex with Inhibitors: A Serine/Threonine Kinase with Tyrosine as a Gatekeeper

Zhulun Wang, Jinsong Liu, Athena Sudom et al. · Structure · 2006 · 145 citations · Full text

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Structure-Based design of 2-Arylamino-4-cyclohexylmethyl-5-nitroso-6-aminopyrimidine inhibitors of cyclin-Dependent kinases 1 and 2

Kerry L. Sayle, Johanne Bentley, F.Thomas Boyle et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 71 citations · Full text

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Synthesis and SAR of aminopyrimidines as novel c-Jun N-terminal kinase (JNK) inhibitors

Mahbub Alam, Rebekah E. Beevers, Tom Ceska et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 61 citations · Full text

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IRAK-4 inhibitors. Part III: A series of imidazo[1,2-a]pyridines

George M. Buckley, Richard Fosbeary, Joanne L. Fraser et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 51 citations · Full text

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A novel series of potent and selective IKK2 inhibitors

Alistair H.A. Bingham, Richard Davenport, Lewis Gowers et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 48 citations · Full text

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