Novel 7-methoxy-6-oxazol-5-yl-2,3-dihydro-1H-quinazolin-4-ones as IMPDH inhibitors

Helen L. Birch, George M. Buckley, Natasha Davies, +15

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBiochemistryMedicineNatural SciencesPharmacological Agent +6

IRAK-4 inhibitors. Part II: A structure-based assessment of imidazo[1,2-a]pyridine binding

George M. Buckley, T.A. Ceska, Joanne L. Fraser, +11

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryDrug TargetBioorganic ChemistryBiochemistryIrak-4 Inhibitors +9

IRAK-4 inhibitors. Part III: A series of imidazo[1,2-a]pyridines

George M. Buckley, Richard Fosbeary, Joanne L. Fraser, +11

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBioorganic ChemistryIrak-4 InhibitorsMedicineNatural Sciences +6

Quinazolinethiones and quinazolinediones, novel inhibitors of inosine monophosphate dehydrogenase: synthesis and initial structure–activity relationships

George M. Buckley, Natasha Davies, Hazel J. Dyke, +12

Bioorganic & Medicinal Chemistry Letters

Initial Structure–activity RelationshipsBiosynthesisBiochemistryMedicineNovel Inhibitors +6

Pain management following major intracranial surgery in pediatric patients: a prospective cohort study in three academic children's hospitals

Lynne G. Maxwell, George M. Buckley, Sapna R. Kudchadkar, +7

Pediatric Anesthesia

IRAK-4 inhibitors. Part 1: A series of amides

George M. Buckley, Lewis Gowers, Alícia P. Higueruelo, +9

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBiochemistryIrak-4 InhibitorsMedicineNatural Sciences +6

8-Methoxyquinolines as PDE4 inhibitors

Motasim Billah, George M. Buckley, Nicola J. Cooper, +17

Bioorganic & Medicinal Chemistry Letters

Pde4 InhibitorsMolecular PharmacologyMedicinal ChemistryBiochemistryMedicine +5

Aryl sulfonamides as selective PDE4 inhibitors

John G. Montana, George M. Buckley, Nicola Cooper, +12

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryNatural SciencesMedicineChemistryAryl Sulfonamides +3

7-Methoxyfuro[2,3-c]pyridine-4-carboxamides as PDE4 Inhibitors: A Potential Treatment for Asthma

George M. Buckley, Nicola J. Cooper, Richard Davenport, +14

Bioorganic & Medicinal Chemistry Letters

AsthmaPde4 InhibitorsMedicinal ChemistryAllergyMedicine +5

Low molecular weight indole fragments as IMPDH inhibitors

Rebekah E. Beevers, George M. Buckley, Natasha Davies, +12

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryMedicineMechanism Of ActionPharmacologyPharmaceutical Chemistry +3