Concepedia

DNA-binding affinity and anticancer activity of β-carboline–chalcone conjugates as potential DNA intercalators: Molecular modelling and synthesis

Nagula Shankaraiah, K P Siraj, Shalini Nekkanti, Vunnam Srinivasulu, Pankaj Sharma, Kishna Ram Senwar, Manda Sathish, M.V.P.S. Vishnuvardhan, Ramakrishna Sistla, Jadala Chetna,

Bioorganic Chemistry · 2015 · 100 citations · 29 references

DOI

Concepts

References

29

Mechanism of ethidium bromide fluorescence enhancement on binding to nucleic acids

J. Olmsted, David R. Kearns · Biochemistry · 1977 · 563 citations

, , +11

Criteria for the mode of binding of DNA binding agents

Dongchul Suh, Jonathan B. Chaires · Bioorganic & Medicinal Chemistry · 1995 · 464 citations

, , +10

Interactions of antitumor drugs with natural DNA: proton NMR study of binding mode and kinetics

Juli Feigon, William A. Denny, Werner Leupin et al. · Journal of Medicinal Chemistry · 1984 · 280 citations

, , +10

Novel IKK inhibitors: β-carbolines

Alfredo Castro, François Soucy, Louis Grenier et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 241 citations · Full text

, , +7

Specific inhibition of cyclin-dependent kinases and cell proliferation by harmine

Yongcheng Song, Djohan Kesuma, Jian Wang et al. · Biochemical and Biophysical Research Communications · 2004 · 179 citations

, , +16