A Cholesterol Biosynthesis Inhibitor Blocks <i>Staphylococcus aureus</i> Virulence

Chia-I Liu, George Y. Liu, Yongcheng Song, +6

Science

Cholesterol BiosynthesisStaphyloxanthin BiosynthesisBiosynthesisAntimicrobial SusceptibilityHealth Sciences +12

Regioselective Radical Aminofluorination of Styrenes

Hongwei Zhang, Yongcheng Song, Jinbo Zhao, +2

Angewandte Chemie International Edition

An epigenomic approach to therapy for tamoxifen-resistant breast cancer

Qin Feng, Zheng Zhang, Martin J. Shea, +15

Cell Research

Breast OncologyCancer BiologyMammary Gland DevelopmentTumor BiologyOncology +17

Bisphosphonates target multiple sites in both <i>cis</i> - and <i>trans</i> -prenyltransferases

Rey‐Ting Guo, Rong Cao, Po‐Huang Liang, +11

Proceedings of the National Academy of Sciences

Drug TargetMolecular BiologyChemical BiologyFpps InhibitionMolecular Pharmacology +15

Specific inhibition of cyclin-dependent kinases and cell proliferation by harmine

Yongcheng Song, Djohan Kesuma, Jian Wang, +4

Biochemical and Biophysical Research Communications

Specific InhibitionSignal TransductionMedicineMechanism Of ActionPharmacotherapy +5

Lipophilic Bisphosphonates as Dual Farnesyl/Geranylgeranyl Diphosphate Synthase Inhibitors: An X-ray and NMR Investigation

Yonghui Zhang, Rong Cao, Fenglin Yin, +21

Journal of the American Chemical Society

Medicinal ChemistryNmr InvestigationBiochemistryMedicineNatural Sciences +12

Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in <i>Toxoplasma gondii</i>

Sethu C. Nair, Carrie F. Brooks, C.D. Goodman, +7

The Journal of Experimental Medicine

Antiparasitic AgentMalariaImmunologyFosmidomycin ResistanceMolecular Biology +15

Selective Inhibitors of Histone Methyltransferase DOT1L: Design, Synthesis, and Crystallographic Studies

Yuan Yao, Pinhong Chen, Jiasheng Diao, +5

Journal of the American Chemical Society

β-Carbolines as specific inhibitors of cyclin-Dependent kinases

Yongcheng Song, Jian Wang, Su Fern Teng, +6

Bioorganic & Medicinal Chemistry Letters

Cyclin-dependent KinasesBiochemistryMedicineMechanism Of ActionPharmacological Agent +3

GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex

Bin He, Rainer B. Lanz, Warren Fiskus, +24

Proceedings of the National Academy of Sciences