Alfredo Castro - Concepedia

Author

Alfredo Castro

Infinity Pharmaceuticals (United States)ORCID

Also Known As

Alfredo C Castro, Alfredo C. Castro, Alfredo Castro, Julien Bachelier

Publications

2.7K

Citations

H-Index

Concepts

All Affiliations

Infinity Pharmaceuticals (United States)Millennium Engineering and Integration (United States)Ciena (United States)

About

Alfredo Castro is an author at Infinity Pharmaceuticals (United States) specializing in medicine, drug discovery, and pharmacology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	8	8	1.1K
2	Cell Biology	4	4	338
3	Natural Sciences	2	2	321
4	Biochemistry	2	2	321
5	Allergy	1	1	207

Alfredo Castro

Publications

2.5K

Citations

H-Index

Page 1

	Year	Citations
NF-κB as a Therapeutic Target in Multiple Myeloma Teru Hideshima, Dharminder Chauhan, Paul G. Richardson, Journal of Biological Chemistry	2002	891
Blockade of the AHR restricts a Treg-macrophage suppressive axis induced by L-Kynurenine Luís Felipe Campesato, Sadna Budhu, Jeremy H. Tchaicha, Nature Communications	2020	418
Discovery of a Potent and Orally Active Hedgehog Pathway Antagonist (IPI-926) Martin Tremblay, André Lescarbeau, Michael J. Grogan, Journal of Medicinal Chemistry Medicinal ChemistryCompound 28Pharmaceutical ScienceChemoprevention StrategyMedicine	2009	250
Novel IKK inhibitors: β-carbolines Alfredo Castro, François Soucy, Louis Grenier, Bioorganic & Medicinal Chemistry Letters Molecular PharmacologyMedicinal ChemistryBiochemistryNovel Ikk InhibitorsMedicine	2003	241
Selective, Tight-Binding Inhibitors of Integrin α4β1 That Inhibit Allergic Airway Responses Ko‐Chung Lin, Humayun S. Ateeq, Sherry H. Hsiung, Journal of Medicinal Chemistry Inflammatory Lung DiseaseLung InflammationApoptosis InhibitionImmunologyPeptide Science	1999	207
Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)-γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate Catherine A. Evans, Tao Liu, André Lescarbeau, ACS Medicinal Chemistry Letters ImmunologyRobust Inhibition-γ InhibitorPharmacotherapyImmuno-oncology Clinical Candidate	2016	146
Semisynthetic Cyclopamine Analogues as Potent and Orally Bioavailable Hedgehog Pathway Antagonists Martin Tremblay, Marta Nevalainen, Somarajan Nair, Journal of Medicinal Chemistry Hedgehog AntagonistsMedicinal ChemistryPharmacological StudyMedicineNew Cyclopamine Analogues	2008	106
Synthetic Silvestrol Analogues as Potent and Selective Protein Synthesis Inhibitors Tao Liu, Somarajan Nair, André Lescarbeau, Journal of Medicinal Chemistry Drug TargetSimplified AnaloguesCompounds 74Molecular BiologyProtein Translation	2012	80
Discovery and Characterization of a Novel Aryl Hydrocarbon Receptor Inhibitor, IK-175, and Its Inhibitory Activity on Tumor Immune Suppression Karen McGovern, Alfredo Castro, Jill Cavanaugh, Molecular Cancer Therapeutics	2022	41
New developments in the discovery of small molecule Hedgehog pathway antagonists Martin Tremblay, Karen McGovern, Margaret Read, Current Opinion in Chemical Biology MedicineNew DevelopmentsNon-peptide LigandDrug DevelopmentPharmacology	2010	34

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