The marine sphingolipid-derived compound ES 285 triggers an atypical cell death pathway

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

Sandeep Robert Datta, Henryk Dudek, Xu Tao et al. · Cell · 1997 · 5.7K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C

Dominique Toullec, P. Pianetti, Hervé Coste et al. · Journal of Biological Chemistry · 1991 · 2.5K citations · Full text

Pharmacy, Biochemistry, Pharmacology +11

Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt

Henryk Dudek, Sandeep Robert Datta, Thomas Franke et al. · Science · 1997 · 2.5K citations

Life Sciences, Neurobiology, Neuroscience +16

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.

Yusuf A. Hannun, Carson R. Loomis, Alfred H. Merrill et al. · Journal of Biological Chemistry · 1986 · 1.2K citations · Full text

Life Sciences, Biochemistry, Pharmacology +15

Lysophosphatidate-induced cell proliferation: Identification and dissection of signaling pathways mediated by G proteins

E.J. van Corven, Alida Groenink, Kees Jalink et al. · Cell · 1989 · 846 citations

Life Sciences, Cell Biology, Molecular Biology +7