Concepedia

Synthesis and SAR studies of a novel class of S1P1 receptor antagonists

Tsuyoshi Nakamura, Kiyoaki Yonesu, Yumiko Mizuno, Chie Suzuki, Yuki Sakata, Yoh Takuwa, Futoshi Nara, Susumu Satoh

Bioorganic & Medicinal Chemistry · 2007 · 14 citations · 17 references

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17

Edg-1, the G protein–coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation

Yujing Liu, Ryuichi Wada, Tadashi Yamashita et al. · Journal of Clinical Investigation · 2000 · 1.1K citations · Full text

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Sphingosine-1-Phosphate as a Ligand for the G Protein-Coupled Receptor EDG-1

Menq-Jer Lee, James R. Van Brocklyn, Shobha Thangada et al. · Science · 1998 · 1K citations

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Dual Actions of Sphingosine-1-Phosphate: Extracellular through the Gi-coupled Receptor Edg-1 and Intracellular to Regulate Proliferation and Survival

James R. Van Brocklyn, Menq-Jer Lee, Ramil Menzeleev et al. · The Journal of Cell Biology · 1998 · 466 citations · Full text

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Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo

Marta Sanna, Sheng‐Kai Wang, Pedro J. Gonzalez‐Cabrera et al. · Nature Chemical Biology · 2006 · 401 citations · Full text

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Sphingosine 1-Phosphate Induces Angiogenesis: Its Angiogenic Action and Signaling Mechanism in Human Umbilical Vein Endothelial Cells

Ok-Hee Lee, Youngmi Kim, Eun-Joung Moon et al. · Biochemical and Biophysical Research Communications · 1999 · 368 citations

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