James R. Van Brocklyn

Sphingosine-1-Phosphate as a Ligand for the G Protein-Coupled Receptor EDG-1

Menq-Jer Lee, James R. Van Brocklyn, Shobha Thangada et al. · Science · 1998 · 1K citations

Dual Actions of Sphingosine-1-Phosphate: Extracellular through the Gi-coupled Receptor Edg-1 and Intracellular to Regulate Proliferation and Survival

James R. Van Brocklyn, Menq-Jer Lee, Ramil Menzeleev et al. · The Journal of Cell Biology · 1998 · 466 citations · Full text

MicroRNA-451 Regulates LKB1/AMPK Signaling and Allows Adaptation to Metabolic Stress in Glioma Cells

Jakub Godlewski, Michal O. Nowicki, Agnieszka Bronisz et al. · Molecular Cell · 2010 · 423 citations · Full text

Systems Biology, Allows Adaptation, Cell Regulation +12

Sphingosine 1-Phosphate Stimulates Cell Migration through a Gi-coupled Cell Surface Receptor

Fang Wang, James R. Van Brocklyn, John P. Hobson et al. · Journal of Biological Chemistry · 1999 · 371 citations · Full text

Chemoprevention Strategy, Apoptosis, Immunology +17

Sphingosine Kinase-1 Expression Correlates With Poor Survival of Patients With Glioblastoma Multiforme: Roles of Sphingosine Kinase Isoforms in Growth of Glioblastoma Cell Lines

James R. Van Brocklyn, Catherine A. Jackson, Dennis K. Pearl et al. · Journal of Neuropathology & Experimental Neurology · 2005 · 327 citations · Full text

Tumor Innervation, Pathology, Cell Cycle +17