Concepedia

Structures of human insulin-degrading enzyme reveal a new substrate recognition mechanism

Yuequan Shen, A. Joachimiak, Marsha Rich Rosner, Wei‐Jen Tang

Nature · 2006 · 373 citations · 27 references

DOI

Concepts

References

27

<i>Coot</i>: model-building tools for molecular graphics

Paul Emsley, Kevin Cowtan · Acta Crystallographica Section D Biological Crystallography · 2004 · 31.4K citations · Full text

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[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods

Eric de La Fortelle, G. Bricogne · Methods in enzymology on CD-ROM/Methods in enzymology · 1997 · 1.9K citations

, , +14

Insulin-degrading enzyme regulates the levels of insulin, amyloid β-protein, and the β-amyloid precursor protein intracellular domain <i>in vivo</i>

Wesley Farris, Stefan Mansourian, Yang Chang et al. · Proceedings of the National Academy of Sciences · 2003 · 1.5K citations · Full text

, , +15

Shape Complementarity at Protein/Protein Interfaces

Michael C. Lawrence, Peter M. Colman · Journal of Molecular Biology · 1993 · 1.2K citations

, , +14

Enhanced Proteolysis of β-Amyloid in APP Transgenic Mice Prevents Plaque Formation, Secondary Pathology, and Premature Death

Malcolm A. Leissring, Wesley Farris, Alice Y. Chang et al. · Neuron · 2003 · 708 citations · Full text

, , +16