Concepedia

Evaluation of intracellular trafficking and clearance from HeLa cells of doxorubicin-bound block copolymers

Kumiko Sakai‐Kato, Keiko Ishikura, Yuki Oshima, Minoru Tada, Takuo Suzuki, Akiko Ishii‐Watabe, Teruhide Yamaguchi, Nobuhiro Nishiyama, Kazunori Kataoka, Toru Kawanishi,

International Journal of Pharmaceutics · 2011 · 28 citations · 33 references

DOI

Concepts

References

33

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

, , +12

Block copolymer micelles for drug delivery: design, characterization and biological significance

Kazunori Kataoka, Atsushi Harada, Yukio Nagasaki · Advanced Drug Delivery Reviews · 2001 · 3.5K citations

, , +16

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues.

F Thiébaut, T Tsuruo, Hironobu Hamada et al. · Proceedings of the National Academy of Sciences · 1987 · 2.8K citations · Full text

, , +9

Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

Stephen G. Aller, Jodie Yu, Andrew B. Ward et al. · Science · 2009 · 1.9K citations · Full text

, , +12

Reduced cardiotoxicity and comparable efficacy in a phase IIItrial of pegylated liposomal doxorubicin HCl(CAELYX™/Doxil®) versus conventional doxorubicin forfirst-line treatment of metastatic breast cancer

E O’Brien, Nely Wigler, Moshe Inbar et al. · Annals of Oncology · 2004 · 1.7K citations · Full text

, , +17