E O’Brien

Reduced cardiotoxicity and comparable efficacy in a phase IIItrial of pegylated liposomal doxorubicin HCl(CAELYX™/Doxil®) versus conventional doxorubicin forfirst-line treatment of metastatic breast cancer

E O’Brien, Nely Wigler, Moshe Inbar et al. · Annals of Oncology · 2004 · 1.7K citations · Full text

Medicine, Oncology, Pharmacology +17

A randomized trial of late reperfusion therapy for acute myocardial infarction. Thrombolysis and Angioplasty in Myocardial Infarction-6 Study Group.

Eric J. Topol, Robert M. Califf, Michel Vandormael et al. · Circulation · 1992 · 209 citations · Full text

Medicine, Cardiology, Internal Medicine +17

Dietary induced subclinical vitamin K deficiency in normal human subjects.

Guylaine Ferland, James A. Sadowski, E O’Brien · Journal of Clinical Investigation · 1993 · 146 citations · Full text

Agriculture, Nutrition, Nutritional Sciences +13

SRL172 (killed Mycobacterium vaccae) in addition to standard chemotherapy improves quality of life without affecting survival, in patients with advanced non-small-cell lung cancer: phase III results

E O’Brien, Heather Anderson, E. Kaukel et al. · Annals of Oncology · 2004 · 139 citations · Full text

Medicine, Oncology, Pharmacology +14

A randomised trial in malignant mesothelioma (M) of early (E) versus delayed (D) chemotherapy in symptomatically stable patients: the MED trial

E O’Brien, David Watkins, C. Ryan et al. · Annals of Oncology · 2005 · 123 citations · Full text

Medicine, Oncology, Chemotherapy +6