David Watkins

Patient-derived organoids model treatment response of metastatic gastrointestinal cancers

Georgios Vlachogiannis, Somaieh Hedayat, Alexandra Vatsiou et al. · Science · 2018 · 1.9K citations · Full text

High-Level Clonal <i>FGFR</i> Amplification and Response to FGFR Inhibition in a Translational Clinical Trial

Alex Pearson, Elizabeth Smyth, Irina S. Babina et al. · Cancer Discovery · 2016 · 259 citations · Full text

Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer

Andrew Woolston, Khurum Khan, Georgia Spain et al. · Cancer Cell · 2019 · 254 citations · Full text

Tumor Biology, Cetuximab Resistance Landscape, Immune Landscape Evolution +13

Longitudinal Liquid Biopsy and Mathematical Modeling of Clonal Evolution Forecast Time to Treatment Failure in the PROSPECT-C Phase II Colorectal Cancer Clinical Trial

Khurum Khan, David Cunningham, Benjamin Werner et al. · Cancer Discovery · 2018 · 233 citations · Full text

Patients’ willingness to participate in clinical trials and their views on aspects of cancer research: results of a prospective patient survey

Sing Yu Moorcraft, Cheryl Marriott, Clare Peckitt et al. · Trials · 2016 · 209 citations · Full text