Concepedia

Targeting the RAF/MEK/ERK, PI3K/AKT and P53 pathways in hematopoietic drug resistance

James A. McCubrey, Linda S. Steelman, Richard A. Franklin, Steven L. Abrams, William H. Chappell, Ellis W.T. Wong, Brian D. Lehmann, David M. Terrian, Jörg Bäsecke, Franca Stivala,

Advances in Enzyme Regulation · 2007 · 90 citations · 218 references

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218

Mutations of the BRAF gene in human cancer

Helen Davies, Graham R. Bignell, Charles Cox et al. · Nature · 2002 · 10.7K citations

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Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor

Anne Brunet, Azad Bonni, Michael J. Zigmond et al. · Cell · 1999 · 6.6K citations · Full text

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Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

Sandeep Robert Datta, Henryk Dudek, Xu Tao et al. · Cell · 1997 · 5.7K citations · Full text

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<i>PTEN</i> , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

Jing Li, Clifford Yen, Danny Liaw et al. · Science · 1997 · 4.8K citations

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Regulation of Cell Death Protease Caspase-9 by Phosphorylation

Michael H. Cardone, Natalie Roy, Henning R. Stennicke et al. · Science · 1998 · 3.1K citations

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