5-Arylidene-2,4-thiazolidinediones as inhibitors of protein tyrosine phosphatases

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

Ulrich K. Laemmli · Nature · 1970 · 251.6K citations

Life Sciences, Microbiology, Molecular Biology +14

Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia

Marco Tartaglia, Charlotte M. Niemeyer, Alessandra Fragale et al. · Nature Genetics · 2003 · 1K citations

Medicine, Genetics, Molecular Genetics +17

A Phosphatase Associated with Metastasis of Colorectal Cancer

Saurabh Saha, Alberto Bardelli, Phillip Buckhaults et al. · Science · 2001 · 645 citations

Medicine, Genetics, Oncology +13

The Structure−Activity Relationship between Peroxisome Proliferator-Activated Receptor γ Agonism and the Antihyperglycemic Activity of Thiazolidinediones

Timothy M. Willson, Jeffery E. Cobb, David J. Cowan et al. · Journal of Medicinal Chemistry · 1996 · 639 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Allosteric inhibition of protein tyrosine phosphatase 1B

Christian Wiesmann, Kenneth J. Barr, Jenny Kung et al. · Nature Structural & Molecular Biology · 2004 · 530 citations

Life Sciences, Biochemistry, Molecular Biology +14