The phosphodiesterase-4 inhibitor rolipram protects from ischemic stroke in mice by reducing blood–brain-barrier damage, inflammation and thrombosis

Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.

Joshua B. Bederson, L H Pitts, Masahiko Tsuji et al. · Stroke · 1986 · 2.7K citations

Life Sciences, Neurology, Neuroscience +16

cAMP and Schwann cells promote axonal growth and functional recovery after spinal cord injury

Damien D. Pearse, Francisco C. Pereira, Alexander Marcillo et al. · Nature Medicine · 2004 · 722 citations

Medicine, Neurobiology, Neuroscience +17

The gene encoding phosphodiesterase 4D confers risk of ischemic stroke

Sólveig Grétarsdóttir, Sigridur Th. Reynisdottir, Andrei Manolescu et al. · Nature Genetics · 2003 · 575 citations

Life Sciences, Genetics, Molecular Genetics +13

Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis

Christoph Kleinschnitz, Guido Stoll, Martin Bendszus et al. · The Journal of Experimental Medicine · 2006 · 449 citations · Full text

Medicine, Neuroscience, Pathobiology +17

Post-Stroke Inhibition of Induced NADPH Oxidase Type 4 Prevents Oxidative Stress and Neurodegeneration

Christoph Kleinschnitz, Henrike Grund, Kirstin Wingler et al. · PLoS Biology · 2010 · 438 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17