Concepedia

Phospho Switch Triggers Brd4 Chromatin Binding and Activator Recruitment for Gene-Specific Targeting

Shwu‐Yuan Wu, A-Young Lee, Hsien‐Tsung Lai, Hong Zhang, Cheng‐Ming Chiang

Molecular Cell · 2013 · 347 citations · 27 references

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References

27

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

Jake Delmore, Ghayas C. Issa, Madeleine E. Lemieux et al. · Cell · 2011 · 2.8K citations · Full text

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A variant of yellow fluorescent protein with fast and efficient maturation for cell-biological applications

Takeharu Nagai, Keiji Ibata, Eun Sun Park et al. · Nature Biotechnology · 2002 · 2.8K citations

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RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

Johannes Zuber, Junwei Shi, Eric Wang et al. · Nature · 2011 · 1.9K citations

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Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family

P. Filippakopoulos, S. Picaud, Maria Mangos et al. · Cell · 2012 · 1.8K citations · Full text

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Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

Mark A. Dawson, Rab K. Prinjha, Antje Dittmann et al. · Nature · 2011 · 1.5K citations · Full text

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