NAD+-dependent SIRT1 Deacetylase Participates in Epigenetic Reprogramming during Endotoxin Tolerance

Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase

Fan Yeung, Jamie E. Hoberg, C S Ramsey et al. · The EMBO Journal · 2004 · 2.6K citations · Full text

Gene-specific control of inflammation by TLR-induced chromatin modifications

Simmie L. Foster, Diana C. Hargreaves, Ruslan Medzhitov · Nature · 2007 · 1.3K citations

Inflammation, Tlr-induced Chromatin Modifications, Cytokine +7

Circadian Control of the NAD ⁺ Salvage Pathway by CLOCK-SIRT1

Yasukazu Nakahata, Saurabh Sahar, Giuseppe Astarita et al. · Science · 2009 · 1.2K citations · Full text

Molecular Regulation, Genetics, Homeostatic Mechanism +20

SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span

Tiara L.A. Kawahara, Eriko Michishita, Adam S. Adler et al. · Cell · 2009 · 1.1K citations · Full text

Histone Modifications, Chromatin, Transcriptional Regulation +15

FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis.

Max Hasmann, Isabel Schemainda · PubMed · 2003 · 634 citations

Natural Precursor Nicotinamide, Apoptosis, Cell Death +18