Concepedia

Endotoxin Tolerance

Endotoxin Tolerance is a physiological state of reduced responsiveness to lipopolysaccharide-mediated immune activation following prior exposure to endotoxin, characterized by attenuated pro-inflammatory cytokine production in innate immune cells.

897

Publications

63.5K

Citations

3.5K

Authors

923

Institutions

Publications per year

2017–2026

106

Variants

Lps Tolerance

Parents

Publications

897

Unresponsiveness of MyD88-Deficient Mice to Endotoxin

Taro Kawai, Osamu Adachi, Tomohiko Ogawa et al. · Immunity · 1999 · 2.1K citations · Full text

, , +8

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

Nancy C. Arbour, Eva Lorenz, Brian C. Schutte et al. · Nature Genetics · 2000 · 2K citations

, , +10

Environmental Exposure to Endotoxin and Its Relation to Asthma in School-Age Children

Charlotte Braun‐Fahrländer, Josef Riedler, Udo Herz et al. · New England Journal of Medicine · 2002 · 1.8K citations · Full text

, , +16

Endotoxin-tolerant Mice Have Mutations in Toll-like Receptor 4 (<i>Tlr4</i>)

Salman T. Qureshi, Line Larivière, Gary Leveque et al. · The Journal of Experimental Medicine · 1999 · 1.5K citations · Full text

, , +17

Mice deficient in IL-1β-converting enzyme are defective in production of mature IL-1β and resistant to endotoxic shock

Ping Li, Hamish Allen, Subhashis Banerjee et al. · Cell · 1995 · 1.4K citations · Full text

, , +13

1–5 of 897

Authors

3.5K

  1. SN
    Stefanie N. Vogel

    University of Maryland, Baltimore, United States

    21 publications · 2.2K citations

    19

    h-index

  2. CE
    Charles E. McCall

    Wake Forest University, United States

    22 publications · 2.4K citations

    19

    h-index

  3. JA
    James A. Cook

    Medical University of South Carolina, United States

    21 publications · 990 citations

    17

    h-index

  4. SE
    Sheldon E. Greisman

    University of Maryland, Baltimore, United States

    19 publications · 984 citations

    16

    h-index

  5. PV
    Perry V. Halushka

    Medical University of South Carolina, United States

    15 publications · 464 citations

    15

    h-index

1–5 of 3.5K

Institutions

923

  1. Wake Forest University

    Winston-Salem, United States

    21 h-index

    73 publications

    7.7K citations

  2. University of Maryland, Baltimore

    Baltimore, United States

    21 h-index

    83 publications

    5.7K citations

  3. University of Minnesota

    Minneapolis, United States

    19 h-index

    62 publications

    3.4K citations

  4. Medical University of South Carolina

    Charleston, United States

    18 h-index

    70 publications

    2.8K citations

  5. National Institutes of Health

    Bethesda, United States

    17 h-index

    53 publications

    2.4K citations

  6. Hennepin County Medical Center

    Minneapolis, United States

    14 h-index

    56 publications

    2.2K citations

  7. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    13 h-index

    33 publications

    1.5K citations

  8. Uniformed Services University of the Health Sciences

    Bethesda, United States

    13 h-index

    39 publications

    4.4K citations

1–8 of 923

Venues

  1. The Journal of Immunology

    JI · 68 publications · 7.3K citations

    46

    h-index

  2. Infection and Immunity

    IAI · 53 publications · 3K citations

    31

    h-index

  3. PubMed

    Repository · 67 publications · 3.4K citations

    29

    h-index

  4. The Journal of Experimental Medicine

    29 publications · 5K citations

    26

    h-index

  5. Journal of Biological Chemistry

    JBC · 26 publications · 3.4K citations

    25

    h-index

1–5