Ectopic expression of methionine aminopeptidase-2 causes cell transformation and stimulates proliferation

Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth

Donald E. Ingber, Takeshi Fujita, SHOJI KISHIMOTO et al. · Nature · 1990 · 1.3K citations

Medicine, Oncology, Pharmacology +14

The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2

Ny Sin, Lihao Meng, Margaret Q. W. Wang et al. · Proceedings of the National Academy of Sciences · 1997 · 627 citations

Medicine, Oncology, Pharmacology +13

Structure of Human Methionine Aminopeptidase-2 Complexed with Fumagillin

Shenping Liu, Joanne Widom, Christopher W. Kemp et al. · Science · 1998 · 437 citations

Life Sciences, Biochemistry, Pharmacology +15

Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin

Eric C. Griffith, Zhuang Su, Benjamin E. Turk et al. · Chemistry & Biology · 1997 · 414 citations · Full text

Medicine, Oncology, Pharmacology +9

Characterization of the c-MYC-regulated transcriptome by SAGE: Identification and analysis of c-MYC target genes

Antje Menssen, Heiko Hermeking · Proceedings of the National Academy of Sciences · 2002 · 402 citations · Full text

Life Sciences, Genetics, Molecular Biology +17