Zhuang Su

Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin

Eric C. Griffith, Zhuang Su, Benjamin E. Turk et al. · Chemistry & Biology · 1997 · 414 citations · Full text

Angiogenesis Inhibitors Agm-1470, Angiogenesis, Medicine +9

Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2

Eric C. Griffith, Zhuang Su, Satomi Niwayama et al. · Proceedings of the National Academy of Sciences · 1998 · 258 citations · Full text

Molecular Recognition, Reactive Epoxide Groups, Angiogenesis +13

Synthetic analogues of TNP-470 and ovalicin reveal a common molecular basis for inhibition of angiogenesis and immunosuppression

Benjamin E. Turk, Zhuang Su, Jun O. Liu · Bioorganic & Medicinal Chemistry · 1998 · 52 citations

Biosynthesis of the Unusual Amino Acid (4<i>R</i>)-4-[(<i>E</i>)-2-Butenyl]-4-methyl-<scp>l</scp>-threonine of Cyclosporin A:  Enzymatic Analysis of the Reaction Sequence Including Identification of the Methylation Precursor in a Polyketide Pathway

Manuela Offenzeller, Gerhard Santer, Klaus Totschnig et al. · Biochemistry · 1996 · 42 citations

Engineering, Molecular Biology, Cyclosporin A +18

Biosynthesis of the unusual amino acid (4R)-4-[(E)-2-butenyl]-4-methyl-L-threonine of cyclosporin A. Identification of 3(R)-hydroxy-4(R)-methyl-6(E)-octenoic acid as a key intermediate by enzymatic in vitro synthesis and by in vivo labeling techniques.

Manuela Offenzeller, Zhuang Su, Gerhard Santer et al. · Journal of Biological Chemistry · 1993 · 36 citations · Full text

Key Intermediate, Engineering, Bmt Backbone +16