Concepedia

Manuela Offenzeller

MO

2

Publications

78

Citations

2

H-Index

1993

Active since

Affiliations

Jain PharmaBiotech (Switzerland)(Current)

Manuela Offenzeller is an author at Jain PharmaBiotech (Switzerland) specializing in biosynthesis, engineering, and biocatalysis.

Top concepts

EngineeringBiocatalysisBiochemistryBiosynthesisNatural SciencesPharmacologyChemical BiologyMolecular BiologyProtein SynthesisSynthetic Biology

Publications per year

1993–1996

2

Publications

2

Biosynthesis of the Unusual Amino Acid (4<i>R</i>)-4-[(<i>E</i>)-2-Butenyl]-4-methyl-<scp>l</scp>-threonine of Cyclosporin A: Enzymatic Analysis of the Reaction Sequence Including Identification of the Methylation Precursor in a Polyketide Pathway

Manuela Offenzeller, Gerhard Santer, Klaus Totschnig et al. · Biochemistry · 1996 · 42 citations

Engineering, Molecular Biology, Cyclosporin A +18

Biosynthesis of the unusual amino acid (4R)-4-[(E)-2-butenyl]-4-methyl-L-threonine of cyclosporin A. Identification of 3(R)-hydroxy-4(R)-methyl-6(E)-octenoic acid as a key intermediate by enzymatic in vitro synthesis and by in vivo labeling techniques.

Manuela Offenzeller, Zhuang Su, Gerhard Santer et al. · Journal of Biological Chemistry · 1993 · 36 citations · Full text

Key Intermediate, Engineering, Bmt Backbone +16

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