Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene

Initial sequencing and analysis of the human genome

Eric S. Lander, Lauren Linton, Bruce W. Birren et al. · Nature · 2001 · 24.3K citations · Full text

Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

Manuel Serrano, Athena W. Lin, Mila E. McCurrach et al. · Cell · 1997 · 5K citations · Full text

Developmental Biology, Oncogenic Agent, Cellular Senescence +6

Tissue microarrays for high-throughput molecular profiling of tumor specimens

Juha Kononen, Lukas Bubendorf, Anne Kallionimeni et al. · Nature Medicine · 1998 · 4.1K citations

Engineering, Tumor Heterogeneity, Computational Biology +6

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

Thomas G. Graeber, Cynthia Osmanian, Tyler Jacks et al. · Nature · 1996 · 2.3K citations

Tumor Biology, Hypoxia-mediated Selection, Redox Regulator +11

Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumors

Jonathan R. Pollack, Thérese Sørlie, Charles M. Perou et al. · Proceedings of the National Academy of Sciences · 2002 · 1.1K citations · Full text

Human Breast Tumors, Breast Oncology, Genetics +17