HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune-based therapies

Age, Thymopoiesis, and CD4+ T-Lymphocyte Regeneration after Intensive Chemotherapy

Crystal L. Mackall, Thomas A. Fleisher, Margaret R. Brown et al. · New England Journal of Medicine · 1995 · 1.1K citations · Full text

Life Sciences, Cell Biology, Immunology +15

In vivo emergence of HIV-1 variants resistant to multiple protease inhibitors

Jon H. Condra, William A. Schleif, O M Blahy et al. · Nature · 1995 · 979 citations

Life Sciences, Infectious Diseases, Molecular Biology +16

Interaction of Staphylococcus aureus toxin "superantigens" with human T cells.

Yongwon Choi, Brian L. Kotzin, Lissa R. Herron et al. · Proceedings of the National Academy of Sciences · 1989 · 975 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Human memory T lymphocytes express increased levels of three cell adhesion molecules (LFA-3, CD2, and LFA-1) and three other molecules (UCHL1, CDw29, and Pgp-1) and have enhanced IFN- <i>gamma</i> production.

Martin E. Sanders, Malegapuru W. Makgoba, Susan O. Sharrow et al. · The Journal of Immunology · 1988 · 912 citations

Life Sciences, Cell Biology, Immunology +13

Turnover of naive- and memory-phenotype T cells.

David F. Tough, Jonathan Sprent · The Journal of Experimental Medicine · 1994 · 870 citations · Full text

Life Sciences, Cell Biology, Immunology +15