Proceedings of the National Academy of Sciences · 1989 · 975 citations · 34 references
Life SciencesImmunologyMolecular BiologyCellular ImmunologyHost-pathogen InteractionsMolecular ImmunologyAntigen RecognitionBacterial ToxinsCell-mediated ImmunityCytotoxic T Lymphocyte ResponsesT Cell ActivationT Cell BiologyBacterial SuperantigensSuperantigen RecognitionT Cell Receptor StructureT Cell ReceptorsT Cell Responses To Bacterial InfectionT Cell-target Cell InteractionsToxin ReceptorsToxin-host Cell Interactions
A modification of the polymerase chain reaction has been used to establish the fact that a collection of Staphylococcus aureus toxins are "superantigens," each of which interacts with the T-cell alpha beta receptor of human T cells by means of a specific set of V beta elements.
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Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase
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A simple and very efficient method for generating cDNA libraries
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Structure of the human class I histocompatibility antigen, HLA-A2
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T cell tolerance by clonal elimination in the thymus
John W. Kappler, Neal W. Roehm, Philippa Marrack · Cell · 1987 · 2.2K citations