PI3Kγ inhibition reduces blood pressure by a vasorelaxant Akt/L-type calcium channel mechanism - Concepedia

Concepedia

Publication | Open Access

PI3Kγ inhibition reduces blood pressure by a vasorelaxant Akt/L-type calcium channel mechanism

DOI Full Paper Access

43

Citations

20

References

2011

Year

Daniela Carnevale, Carmine Vecchione, Giada Mascio, Giovanni Esposito, Giuseppe Cifelli, Katiuscia Martinello, Alessandro Landolfi, Giulio Selvetella, Paolo Grieco, Antonio Damato,

Cardiovascular Research

Abstract

Overall our findings suggest that PI3Kγ inhibition could be a novel tool to modulate calcium influx in vascular smooth muscle cells, thus relaxing resistance arteries and lowering blood pressure.

References

	Year	Citations

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