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Regulation of Myocardial Contractility and Cell Size by Distinct PI3K-PTEN Signaling Pathways

Michael A. Crackower, Gavin Y. Oudit, I. Kozieradzki, Renu Sarao, Hui Sun, Takehiko Sasaki, Emilio Hirsch, Akira Suzuki, Tetsuo Shioi, Junko Irie-Sasaki,

Cell · 2002 · 578 citations · 36 references

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36

The Tumor Suppressor, PTEN/MMAC1, Dephosphorylates the Lipid Second Messenger, Phosphatidylinositol 3,4,5-Trisphosphate

Tomohiko Maehama, Jack E. Dixon · Journal of Biological Chemistry · 1998 · 3.1K citations · Full text

, , +17

Angiotensin-converting enzyme 2 is an essential regulator of heart function

Michael A. Crackower, Renu Sarao, Gavin Y. Oudit et al. · Nature · 2002 · 1.8K citations

, , +10

Pten is essential for embryonic development and tumour suppression

Antonio Di Cristofano, Bárbara Pesce, Carlos Cordon‐Cardo et al. · Nature Genetics · 1998 · 1.5K citations

, , +14

Direct Regulation of the <i>Akt</i> Proto-Oncogene Product by Phosphatidylinositol-3,4-bisphosphate

T. Franke, David R. Kaplan, Lewis C. Cantley et al. · Science · 1997 · 1.5K citations

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Inhibition of Cell Migration, Spreading, and Focal Adhesions by Tumor Suppressor PTEN

Masahito Tamura, Jianguo Gu, Kazue Matsumoto et al. · Science · 1998 · 1.2K citations

, , +17