Concepedia

The Parkin-Like Human Homolog of Drosophila Ariadne-1 (HHARI) Can Induce Aggresome Formation in Mammalian Cells and Is Immunologically Detectable in Lewy Bodies

Sangram S. Parelkar, Juan G. Cadena, Chul Kim, Zhaohui Wang, Rachel Sugal, Brooke Bentley, Luis Moral, H.C. Ardley, Lawrence M. Schwartz

Journal of Molecular Neuroscience · 2011 · 20 citations · 46 references

DOI

Concepts

References

46

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

Tohru Kitada, Shuichi Asakawa, Nobutaka Hattori et al. · Nature · 1998 · 5.2K citations

, , +10

Aggresomes: A Cellular Response to Misfolded Proteins

Jennifer Johnston, Cristina L. Ward, Ron R. Kopito · The Journal of Cell Biology · 1998 · 2.2K citations · Full text

, , +17

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

Montserrat Arrasate, Siddhartha Mitra, Erik S. Schweitzer et al. · Nature · 2004 · 2K citations

, , +15

Accelerated in vitro fibril formation by a mutant α-synuclein linked to early-onset Parkinson disease

Kelly A. Conway, James D. Harper, Peter T. Lansbury · Nature Medicine · 1998 · 1.5K citations

, , +16

Parkin functions as an E2-dependent ubiquitin– protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1

Yi Zhang, Jun Gao, Kenny K. K. Chung et al. · Proceedings of the National Academy of Sciences · 2000 · 979 citations · Full text

, , +17